YHR043C

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Systematic name YHR043C
Gene name DOG2
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:193538..192798
Primary SGDID S000001085


Description of YHR043C: 2-deoxyglucose-6-phosphate phosphatase, member of a family of low molecular weight phosphatases, similar to Dog1p, induced by oxidative and osmotic stress, confers 2-deoxyglucose resistance when overexpressed[1][2][3]




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References

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  1. Tsujimoto Y, et al. (2000) Cooperative regulation of DOG2, encoding 2-deoxyglucose-6-phosphate phosphatase, by Snf1 kinase and the high-osmolarity glycerol-mitogen-activated protein kinase cascade in stress responses of Saccharomyces cerevisiae. J Bacteriol 182(18):5121-6 SGD PMID 10960096
  2. Norbeck J, et al. (1996) Purification and characterization of two isoenzymes of DL-glycerol-3-phosphatase from Saccharomyces cerevisiae. Identification of the corresponding GPP1 and GPP2 genes and evidence for osmotic regulation of Gpp2p expression by the osmosensing mitogen-activated protein kinase signal transduction pathway. J Biol Chem 271(23):13875-81 SGD PMID 8662716
  3. Randez-Gil F, et al. (1995) DOGR1 and DOGR2: two genes from Saccharomyces cerevisiae that confer 2-deoxyglucose resistance when overexpressed. Yeast 11(13):1233-40 SGD PMID 8553694

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