YDR432W

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Systematic name YDR432W
Gene name NPL3
Aliases MTR13, MTS1, NAB1, NOP3
Feature type ORF, Verified
Coordinates Chr IV:1328776..1330020
Primary SGDID S000002840


Description of YDR432W: RNA-binding protein that carries poly(A)+ mRNA from the nucleus into the cytoplasm; dissociation from mRNAs is promoted by Mtr10p; phosphorylated by Sky1p in the cytoplasm[1][2][3]




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References

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  1. Windgassen M, et al. (2004) Yeast shuttling SR proteins Npl3p, Gbp2p, and Hrb1p are part of the translating mRNPs, and Npl3p can function as a translational repressor. Mol Cell Biol 24(23):10479-91 SGD PMID 15542855
  2. Gilbert W, et al. (2001) Phosphorylation by Sky1p promotes Npl3p shuttling and mRNA dissociation. RNA 7(2):302-13 SGD PMID 11233987
  3. Lee MS, et al. (1996) A protein that shuttles between the nucleus and the cytoplasm is an important mediator of RNA export. Genes Dev 10(10):1233-46 SGD PMID 8675010

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