tL(UAA)Q

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Systematic name tL(UAA)Q
Gene name
Aliases
Feature type tRNA
Coordinates Mito:66095..66179
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Description of tL(UAA)Q: Mitochondrial tRNA-Leu, required for mitochondrial translation and indirectly for maintenance of the mitochondrial genome; mutations in the orthologous human gene cause the neurological disease MELAS[1]



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References

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  1. ↑ Feuermann M, et al. (2003) The yeast counterparts of human 'MELAS' mutations cause mitochondrial dysfunction that can be rescued by overexpression of the mitochondrial translation factor EF-Tu. EMBO Rep 4(1):53-8 SGD PMID 12524521

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