S000000052

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Systematic name YAL056W
Gene name GPB2
Aliases KRH1
Feature type ORF, Verified
Coordinates Chr I:39260..41902


Description of S000000052: Proposed beta subunit of the heterotrimeric G protein; interacts with the receptor Grp1p, affects signaling by altering the level of phosphorylation of PKS substrates; regulates pseudohyphal growth through cAMP levels; homolog of Gpb1p[1][2]




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References

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  1. Lu A and Hirsch JP (2005) Cyclic AMP-independent regulation of protein kinase A substrate phosphorylation by Kelch repeat proteins. Eukaryot Cell 4(11):1794-800 SGD PMID 16278446
  2. Harashima T and Heitman J (2002) The Galpha protein Gpa2 controls yeast differentiation by interacting with kelch repeat proteins that mimic Gbeta subunits. Mol Cell 10(1):163-73 SGD PMID 12150916

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