YPR070W

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Systematic name YPR070W
Gene name MED1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:685895..687595


Description of YPR070W: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation[1][2]




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References

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  1. Kornberg RD (2005) Mediator and the mechanism of transcriptional activation. Trends Biochem Sci 30(5):235-9 SGD PMID 15896740
  2. Balciunas D, et al. (1999) The Med1 subunit of the yeast mediator complex is involved in both transcriptional activation and repression. Proc Natl Acad Sci U S A 96(2):376-81 SGD PMID 9892641

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