YOR316C

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Systematic name YOR316C
Gene name COT1
Aliases
Feature type ORF, Verified
Coordinates Chr XV:907552..906233


Description of YOR316C: Vacuolar transporter that mediates zinc transport into the vacuole; overexpression confers resistance to cobalt and rhodium[1][2][3]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in sulfur limited chemostat cultures versus sulfur excess. [4] [5]




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References

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  1. Li L and Kaplan J (1998) Defects in the yeast high affinity iron transport system result in increased metal sensitivity because of the increased expression of transporters with a broad transition metal specificity. J Biol Chem 273(35):22181-7 SGD PMID 9712830
  2. Conklin DS, et al. (1992) COT1, a gene involved in cobalt accumulation in Saccharomyces cerevisiae. Mol Cell Biol 12(9):3678-88 SGD PMID 1508175
  3. MacDiarmid CW, et al. (2000) Zinc transporters that regulate vacuolar zinc storage in Saccharomyces cerevisiae. EMBO J 19(12):2845-55 SGD PMID 10856230
  4. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  5. submitted by Viktor Boer on 2003-07-25

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