YLR417W

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Systematic name YLR417W
Gene name VPS36
Aliases GRD12, VAC3, VPL11
Feature type ORF, Verified
Coordinates Chr XII:955007..956707


Description of YLR417W: Component of the ESCRT-II complex; contains the GLUE (GRAM Like Ubiquitin binding in EAP45) domain which is involved in interactions with ESCRT-I and ubiquitin-dependent sorting of proteins into the endosome[1][2]




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References

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  1. Teo H, et al. (2006) ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes. Cell 125(1):99-111 SGD PMID 16615893
  2. Hierro A, et al. (2004) Structure of the ESCRT-II endosomal trafficking complex. Nature 431(7005):221-5 SGD PMID 15329733

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