Details of 2021 Reference Genome Annotation Update R64.3
The S. cerevisiae strain S288C reference genome annotation was updated in its first major update since 2014. The new genome annotation is release R64.3.1, dated 2021-04-22. Note that the underlying genome sequence itself was not altered in any way.
This annotation update included:
- 5 new ncRNAs
- 1 new recombination enhancer
- 7 new ORFs
- 1 new LTR
- 2 new uORFs
- 2 ORFs with shifted translation starts
- 1 ORFs with shifted translation stop
- Changed feature_type (and SO_term) for non-transcribed spacers
- New systematic nomenclature system for entire annotated complement of ncRNAs
| Chr | Feature | Description of change | Reference |
|---|---|---|---|
| II | YNCB0008W aka GAL10-ncRNA | New ncRNA | PMID:19061643, PMID:19407817, PMID:22226051 |
| II | YNCB0014W aka TBRT/XUT_2F-154 | New ncRNA | PMID:32081726 |
| III | RE/RE301 | New recombination enhancer | PMID:8861911 |
| V | YELWdelta27 | New Ty1 LTR | PMID:29320491 |
| V | HPA3/YEL066W | Moved translation start to Met19
old coordinates: 26667..27206 new coordinates: 26721..27206 |
PMID: 23775086 |
| VII | OTO1/YGR227C-A | New ORF | PMID: 25781884 |
| VII | ROK1/YGL171W | Added two new uORFs
uORF1: 182286..182407 uORF2: 182291..182329 |
PMID:20969870 |
| VIII | YHR052C-B | New ORF | PMID:29897761 |
| VIII | YHR054C-B | New ORF | PMID:29897761 |
| VIII | SUT169/YNCH0011W | New ncRNA | PMID:19169243, PMID:22226051, PMID:27292640, PMID:28977638 |
| X | YJR107C-A | New ORF | PMID:26554900, PMID:29897761 |
| X | YJR012C | Moved start to Met76
old coordinates: 459795..460418 Crick new coordinates: 459795..460193 Crick |
PMID:29632376 |
