Details of 2021 Reference Genome Annotation Update R64.3

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The S. cerevisiae strain S288C reference genome annotation was updated in its first major update since 2014. The new genome annotation is release R64.3.1, dated 2021-04-22. Note that the underlying genome sequence itself was not altered in any way.

Chr Feature Description of change Reference
II YNCB0008W aka GAL10-ncRNA New ncRNA PMID:19061643, PMID:19407817, PMID:22226051
II YNCB0014W aka TBRT/XUT_2F-154 New ncRNA PMID:32081726
III RE/RE301 New recombination enhancer PMID:8861911
V YELWdelta27 New Ty1 LTR PMID:29320491
V HPA3/YEL066W Moved translation start to Met19 
old coordinates: 26667..27206
new coordinates: 26721..27206
PMID: 23775086
VII OTO1/YGR227C-A New ORF PMID: 25781884
VII ROK1/YGL171W Added two new uORFs 
uORF1: 182286..182407
uORF2: 182291..182329
PMID:20969870
VIII YHR052C-B New ORF PMID:29897761
VIII YHR054C-B New ORF PMID:29897761
VIII SUT169/YNCH0011W New ncRNA PMID:19169243, PMID:22226051, PMID:27292640, PMID:28977638
X YJR107C-A New ORF PMID:26554900, PMID:29897761
X YJR012C Moved start to Met76 
old coordinates: 459795..460418 Crick
new coordinates: 459795..460193 Crick
PMID:29632376
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