Chromosome I History

Sequence Changes

Date	Affected Features	Start Coordinate of Change	End Coordinate of Change	Type of Change	Old Sequence	New Sequence
2011-02-03	YAL013W	130485	130486	Deletion	GT
	Two nucleotides were deleted near the 3' end of ORF DEP1/YAL013W, altering its coding sequence. The start and most of the reading frame remain the same, but the C-terminus has changed and the annotated protein is now 15 amino acids shorter. New 130445 AGACTCCGAAATCAACGACGACTTCCACCAGTGGGCCCA--GTGACCGCCACACTGGACC 130502 ||||||||||||||||||||||||||||||||||||||| ||||||||||||||||||| Old 130446 AGACTCCGAAATCAACGACGACTTCCACCAGTGGGCCCAGTGTGACCGCCACACTGGACC 130505 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAR019W-A	175305	175305	Insertion		C
	A single C nucleotide was inserted very near the 3' end of ORF YAR019W-A, altering its coding sequence. The start and most of the reading frame remain the same, but the C-terminus has changed and the annotated protein is now 4 amino acids shorter. New 175295 GGCACAGCAAAGTCCGCACAGAGCACTACAGTATAGCATAGAGTGCTAATGAGTTGATAG 175354 ||||||||||||| |||||||||||||||||||||||||||||||||||||||||||||| Old 175293 GGCACAGCAAAGT-CGCACAGAGCACTACAGTATAGCATAGAGTGCTAATGAGTTGATAG 175351 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAL064W	21531	21531	Insertion		A
	A single A nucleotide was inserted within ORF YAL064W, near its 5' end, moving the start codon out of frame with the rest of the protein. The C-terminus and majority of the reading frame remain the same, but the N-terminus has changed and the annotated protein is now 14 amino acids shorter. New 21487 CTATCGATGTGTATACAAACGTACTTCAAATAAGCAATGCGAATATACTGCAACTTTTCG 21546 |||||||||||||||||||||||||||||||||||||||||| ||||||||||||||||| Old 21490 CTATCGATGTGTATACAAACGTACTTCAAATAAGCAATGCGA-TATACTGCAACTTTTCG 21548 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAR014C	167048	167048	Substitution	G	C
		167084	167084	Insertion		C
		167113	167113	Insertion		T
		167133	167133	Insertion		A
		167138	167138	Insertion		T
		167142	167142	Insertion		A
		167149	167149	Insertion		T
		167551	167551	Substitution	G	C
		167802	167802	Substitution	C	T
	Six separate single nucleotides were inserted within ORF BUD14/YAR014C, and three single nucleotide substitutions were also made, altering its coding sequence. The start, stop, and majority of the reading frame remain the same, but the annotated protein is now two amino acids longer and a small section of the protein sequence is now different. New 167033 GTCAGTTTGATTTGCCATTCCTCCACTAGACCCCAAGCTGGCTTGAATTTGCCCCTCTGT 167092 |||||||||||||| |||||||||||||||||||||||||||||||||||| |||||||| Old 167034 GTCAGTTTGATTTGGCATTCCTCCACTAGACCCCAAGCTGGCTTGAATTTG-CCCTCTGT 167092 New 167093 GTTTTCCACGTTTGTTGTCTCTTCAATTTTCGATTTTGCATGAATATATTGTGAAATGTC 167152 ||||||||||||||||||||| |||||||||||||||||||| ||||| |||| |||||| Old 167093 GTTTTCCACGTTTGTTGTCTC-TCAATTTTCGATTTTGCATG-ATATA-TGTG-AATGTC 167148 New 167153 CTTTATTGCTCTAGATGATGGAATACTGCTGCTTTCTTCAACTATTGGAGTGGATGGTGA 167212 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||| Old 167149 C-TTATTGCTCTAGATGATGGAATACTGCTGCTTTCTTCAACTATTGGAGTGGATGGTGA 167207 New 167513 GACGTCGCTCACTACATCGCTCGTATCATCATCCTGGAATTTGCCAAAATTTAACTTCGC 167572 ||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||| Old 167508 GACGTCGCTCACTACATCGCTCGTATCATCATCCTGGAATTTGGCAAAATTTAACTTCGC 167567 New 167763 TATCCATTCAGTGCAGGTGTCGGAATTATACTCTCTGCATCACTTTGATTCTTGTTACCA 167822 |||||||||||||||||||||||||||||||||||||||||||| ||||||||||||||| Old 167758 TATCCATTCAGTGCAGGTGTCGGAATTATACTCTCTGCATCACTCTGATTCTTGTTACCA 167817 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAL051W	48772	48772	Substitution	T	A
		49904	49904	Substitution	C	A
		50327	50327	Substitution	C	A
	Nucleotide changes within the coding region of OAF1/YAL051W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 70 is now Arginine rather than Tryptophan, residue 447 is now Glutamine rather than Proline, and residue 588 is now Lysine rather than Threonine. New 48726 CATAATAGGAAAAGAAATAGAATATTGTTTGTCTGCCAGGCTTGTAGGAAGTCAAAAACA 48785 ||||||||||||||||||||||||||||||||||||||||||||| |||||||||||||| Old 48727 CATAATAGGAAAAGAAATAGAATATTGTTTGTCTGCCAGGCTTGTTGGAAGTCAAAAACA 48786 New 49856 AATAATTGATAAATACCCAATACCGAACGATTTTATTTTATTGAGTCAAAGATGTCTAGC 49915 ||||||||||||||||||||||||||||||||||||||||||||||| |||||||||||| Old 49857 AATAATTGATAAATACCCAATACCGAACGATTTTATTTTATTGAGTCCAAGATGTCTAGC 49916 New 50286 AACCGAGTTAGGGGCGATCTAAGCGATATCAATAATCACAAACTTTTGAGAATTCATAAA 50345 |||||||||||||||||||||||||||||||||||||||| ||||||||||||||||||| Old 50287 AACCGAGTTAGGGGCGATCTAAGCGATATCAATAATCACACACTTTTGAGAATTCATAAA 50346 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAL053W	46231	46231	Substitution	C	G
		46833	46833	Substitution	G	A
		47821	47821	Substitution	T	A
		47826	47826	Substitution	C	T
	Nucleotide changes within the coding region of FLC2/YAL053W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 111 is now Cysteine rather than Serine, residue 312 is now Asparagine rather than Aspartic Acid, and residues 641-643 are now NDS rather than IDP. New 46196 TTTGATTTATGTTCCTTGGGCCAAGTATCGCTTTGCCCCCTAAGTGCTGGGCGTATTGAT 46255 |||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||| Old 46197 TTTGATTTATGTTCCTTGGGCCAAGTATCGCTTTCCCCCCTAAGTGCTGGGCGTATTGAT 46256 New 46796 AGTGATTACAATTTTGACACCATTTTAGACGATTCGAATCTGTACACCACTTCTGAGAAG 46855 |||||||||||||||||||||||||||||||||||| ||||||||||||||||||||||| Old 46797 AGTGATTACAATTTTGACACCATTTTAGACGATTCGGATCTGTACACCACTTCTGAGAAG 46856 New 47806 TGGCAAAAACAAAAATGATTCTGAACTGTTTGAATTGAGAAAAGCTGTTATGGACACCAA 47865 |||||||||||||| |||| |||||||||||||||||||||||||||||||||||||||| Old 47807 TGGCAAAAACAAAATTGATCCTGAACTGTTTGAATTGAGAAAAGCTGTTATGGACACCAA 47866 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAR023C	179683	179683	Substitution	T	A
		179761	179761	Substitution	C	A
	The substitution of two nucleotides within the coding region of YAR023C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 20 is now Phenylalanine rather than Valine, and residue 46 is now Phenylalanine rather than Isoleucine. New 179672 ATTGGTCTACTGAATGACCATATCTGAAGGACTACCATAGAGCCACCTAAACATATCCGG 179731 ||||||||||||| |||||||||||||||||||||||||||||||||||||||||||||| Old 179670 ATTGGTCTACTGATTGACCATATCTGAAGGACTACCATAGAGCCACCTAAACATATCCGG 179729 New 179732 ATCACCATGGCAGGGGAGAGAACACCAGAAAACCAAATGTTTGTTAAAGTCGCCAAAATC 179791 ||||||||||||||||||||||||||||||| |||||||||||||||||||||||||||| Old 179730 ATCACCATGGCAGGGGAGAGAACACCAGAAACCCAAATGTTTGTTAAAGTCGCCAAAATC 179789 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAL026C	96838	96838	Deletion	C
		98350	98351	Substitution	CG	GC
		97678	97679	Substitution	CC	GG
		97025	97026	Substitution	AT	TA
		99563	99565	Substitution	ATC	TCG
		96740	96740	Substitution	G	C
		96841	96841	Insertion		C
	Nucleotide changes within the coding region of DRS2/YAL026C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residues 45-46 are now AN rather than GY, residue 450 is now Alanine rather than Arginine, residue 674 is now Proline rather than Glycine, residues 891-892 are now NT rather than KS, residues 953-954 are now GD rather than AS, and residue 987 is now Valine rather than Leucine. New 96716 TTTTAAAAATTTAAATTGGCCAACAGCTATATCAGCTGAACGAGCCGCTTGCATACCTTC 96775 ||||||||||||||||||||||| |||||||||||||||||||||||||||||||||||| Old 96717 TTTTAAAAATTTAAATTGGCCAAGAGCTATATCAGCTGAACGAGCCGCTTGCATACCTTC 96776 New 96826 CGTTGGCACCA-TCGCCAATGGCTAGCAGTAGTGAAGACGACTTTCTTTTTACCATTTTA 96884 ||||||||||| ||| |||||||||||||||||||||||||||||||||||||||||||| Old 96827 CGTTGGCACCACTCG-CAATGGCTAGCAGTAGTGAAGACGACTTTCTTTTTACCATTTTA 96885 New 97005 TCAATGACGAGCGCTAAGGTATTCATATCATGTGTTGACAATTGATGCTCGTTTAGAGCG 97064 ||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||| Old 97006 TCAATGACGAGCGCTAAGGATTTCATATCATGTGTTGACAATTGATGCTCGTTTAGAGCG 97065 New 97665 GTTACAGAGTTTGGTTTACGGATGATAAACTTATACCCTAAATCTGCACCACCTTGAACG 97724 |||||||||||| |||||||||||||||||||||||||||||||||||||||||||||| Old 97666 GTTACAGAGTTTCCTTTACGGATGATAAACTTATACCCTAAATCTGCACCACCTTGAACG 97725 New 98335 AAACTGTGAACAATGCAATAATCTGTCTGTTGATAATTTTCTCAACCGCGGTTCTTTTAA 98394 |||||||||||||| |||||||||||||||||||||||||||||||||||||||||||| Old 98336 AAACTGTGAACAATCGAATAATCTGTCTGTTGATAATTTTCTCAACCGCGGTTCTTTTAA 98395 New 99535 GAAGTACATGACTTGGTGGTATATAATTCGCGTTCGCATGTGAGTTGGTGACCTTTGAAC 99594 ||||||||||||||||||||||||||| |||||||||||||||||||||||||||||| Old 99536 GAAGTACATGACTTGGTGGTATATAATATCCGTTCGCATGTGAGTTGGTGACCTTTGAAC 99595 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAR019C	172425	172425	Insertion		G
		174173	174173	Substitution	G	C
		174187	174188	Substitution	CG	GC
		172434	172434	Deletion	G
	Nucleotide changes within the coding region of CDC15/YAR019C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 316 is now Alanine rather than Arginine, residue 321 is now Alanine rather than Proline, and 900-902 are now KDV rather than NGC. New 172416 GAATTCCTTTTTGGGACATCC-TTGTTCCAGTTGTTGTTTAAAAACTCCGTTATTTGTAC 172474 |||||||||||| |||||||| |||||||||||||||||||||||||||||||||||||| Old 172414 GAATTCCTTTTT-GGACATCCGTTGTTCCAGTTGTTGTTTAAAAACTCCGTTATTTGTAC 172472 New 174165 TCTGCCCAGGCAGCGGGAGCCGCTGCAAGACTGAATTTAGAGGGTGATATATTTAGTTTC 174224 |||||||||| ||||||||||||| |||||||||||||||||||||||||||||||||| Old 174163 TCTGCCCAGGGAGCGGGAGCCGCTCGAAGACTGAATTTAGAGGGTGATATATTTAGTTTC 174222 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAL047C	55746	55746	Substitution	A	G
		55954	55954	Substitution	A	T
	Nucleotide changes within the coding region of SPC72/YAL047C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 302 is now Asparagine rather than Isoleucine. New 55726 TTTCCAAATTGTTTATCAAGACAGATTGCGATTCGATCTTTTCCTTCAGTTGGGAAATCA 55785 ||||||||||||||||||| |||||||||||||||||||||||||||||||||||||||| Old 55727 TTTCCAAATTGTTTATCAAAACAGATTGCGATTCGATCTTTTCCTTCAGTTGGGAAATCA 55786 New 55916 AATGGAATTTATAAATTGATCATATTCTTTGTGCAAATTTTCTATGACAATCTCTAATTG 55975 ||||||||||||||||||||||||||||||||||||| |||||||||||||||||||||| Old 55917 AATGGAATTTATAAATTGATCATATTCTTTGTGCAAAATTTCTATGACAATCTCTAATTG 55976 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAL060W	36120	36120	Substitution	C	A
	A single nucleotide substitution within the coding region of BDH1/YAL060W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 322 is now Aspartic Acid rather than Alanine. New 36106 TATGTTGTCGAAGACTTCGAAGAAGTTGTTCGTGCCATCCACAACGGAGACATCGCCATG 36165 ||||||||||||| |||||||||||||||||||||||||||||||||||||||||||||| Old 36107 TATGTTGTCGAAGCCTTCGAAGAAGTTGTTCGTGCCATCCACAACGGAGACATCGCCATG 36166 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAL010C	134852	134854	Substitution	TTG	ATT
	A single nucleotide substitution within the coding region of MDM10/YAL010C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 272 is now Asparagine rather than Glutamine. New 134813 TGGCCGAATATGTGGAGGATATATGGCCGAATAATGGATTCCAAGATAATGTCAAAGTTA 134872 ||||||||||||||||||||||||||||||||||||| | |||||||||||||||||||| Old 134815 TGGCCGAATATGTGGAGGATATATGGCCGAATAATGGTTGCCAAGATAATGTCAAAGTTA 134874 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAL017W	120442	120442	Substitution	C	G
	A single nucleotide substitution within the coding region of PSK1/YAL017W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 73 is now Glutamic Acid rather than Glutamine. New 120415 CGAATAAAAAGGAAGGTGATGAGTTCGAGCAAAGTTTAAGAGATACATTTGCGAGCTTTC 120474 |||||||||||||||||||||||||| ||||||||||||||||||||||||||||||||| Old 120416 CGAATAAAAAGGAAGGTGATGAGTTCCAGCAAAGTTTAAGAGATACATTTGCGAGCTTTC 120475 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAL020C	113702	113703	Substitution	CG	GC
	The substitution of two nucleotides within the coding region of ATS1/YAL020C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 305 is now Glycine rather than Alanine. New 113685 GCAGTCCAGGCTGGGAGCCCTTTTGCGGGCCGCAGTTGCCATGCTCTCCCCAGCCCCAGC 113744 |||||||||||||||| |||||||||||||||||||||||||||||||||||||||||| Old 113896 GCAGTCCAGGCTGGGACGCCTTTTGCGGGCCGCAGTTGCCATGCTCTCCCCAGCCCCAGC 113745 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAL025C	100399	100399	Substitution	A	C
	A single nucleotide substitution within the coding region of MAK16/YAL025C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 250 is now Glutamic Acid rather than Glutamine. New 100375 GCTTTCACTGTCGCTTTCGCTTTCACTGGCGCTGGAAGCTTCTCTGTCAGAGTCAGCTAA 100434 ||||||||||||||||||||||| |||||||||||||||||||||||||||||||||||| Old 100376 GCTTTCACTGTCGCTTTCGCTTTGACTGGCGCTGGAAGCTTCTCTGTCAGAGTCAGCTAA 100435 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAL056W	40231	40231	Substitution	C	G
		41240	41240	Substitution	A	G
		41664	41664	Substitution	T	G
		41700	41700	Substitution	C	A
		41703	41703	Substitution	C	A
	Nucleotide changes within the coding region of GPB2/YAL056W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 661 is now Valine rather than Isoleucine, residue 802 is now Cysteine rather than Phenylalanine, and residues 814-815 are now ED rather than AA. New 40196 ATTTTTTTGTAGACGGAATAAAGAACTTACCTCCGCCTTTACTACCTCAAGTGATTAATA 40255 |||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||| Old 40197 ATTTTTTTGTAGACGGAATAAAGAACTTACCTCCCCCTTTACTACCTCAAGTGATTAATA 40256 New 41216 ACGATAATTTGGAAAATTATATAGTCAATCCAGGGAGAAAATCGTCATCTATTCCAATGA 41275 ||||||||||||||||||||||| |||||||||||||||||||||||||||||||||||| Old 41217 ACGATAATTTGGAAAATTATATAATCAATCCAGGGAGAAAATCGTCATCTATTCCAATGA 41276 New 41651 TAAGCACGCAGTGTTGGGAAGAACATAAAATTACTCTGTCCAAGAAGGAAGACGATGAGG 41710 |||||||||||| ||||||||||||||||||||||||||||||||||| || |||||||| Old 41652 TAAGCACGCAGTTTTGGGAAGAACATAAAATTACTCTGTCCAAGAAGGCAGCCGATGAGG 41711 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAL059C-A, YAL059W	36814	36814	Substitution	A	C
	A single nucleotide substitution within the coding regions of overlapping ORFs ECM1/YAL059W and YAL059C-A resulted in altered protein sequences for both ORFs. The start, stop, and reading frames remain the same for both proteins, but ECM1/YAL059W protein residue 102 is now Alanine rather than Aspartic Acid, and YAL059C-A protein residue 36 is now Alanine rather than Serine. New 36776 AAGAAGTTAAATAAAAAGGCTCTGGAAGACAAACTGGCCAACTCTATTTCATCCATGGAC 36835 ||||||||||||||||||||||||||||||||||||| |||||||||||||||||||||| Old 36777 AAGAAGTTAAATAAAAAGGCTCTGGAAGACAAACTGGACAACTCTATTTCATCCATGGAC 36836 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	HRA1	99841	99841	Substitution	A	T
	A single nucleotide substitution was made within ncRNA HRA1. New 99825 TTCAACTTAGTGGCATTAAACAGATTTGGGTTTTCTGGCAAAAAAAGCCAATCACGTGAT 99884 ||||||||||||||| |||||||||||||||||||||||||||||||||||||||||||| Old 99826 TTCAACTTAGTGGCAATAAACAGATTTGGGTTTTCTGGCAAAAAAAGCCAATCACGTGAT 99885 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	ARS110, YAR019W-A	175378	175378	Substitution	T	C
		175371	175371	Deletion	T
	A single nucleotide deletion and a single nucleotide substitution were made in the intergenic region between ORF YAR019W-A and ARS110. New 175355 GCCCAATTTTGATTATGCC-TCTTTTCCATACACGACGCCAGAGGACATTATTACATTAC 175413 ||||||||||||||||||| |||||| ||||||||||||||||||||||||||||||||| Old 175352 GCCCAATTTTGATTATGCCTTCTTTTTCATACACGACGCCAGAGGACATTATTACATTAC 175411 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	ARS106, YAL038W	70874	70874	Substitution	A	G
		70794	70794	Substitution	C	G
	Two separate single nucleotide substitutions were made in the intergenic region between ARS106 and ORF CDC19/YAL038W. New 70746 GGTTTTCCGACTTTATTTGAGATGACTTGAGATGTGTGTCAATGCTAGTATTTTGGAGAT 70805 ||||||||||||||||||||||||||||||||||||||||||||||| |||||||||||| Old 70747 GGTTTTCCGACTTTATTTGAGATGACTTGAGATGTGTGTCAATGCTACTATTTTGGAGAT 70806 New 70856 TTATTTTTTTTTTGTTAGAATTGATCCAAATGTAAATAAACAATCACAAGGAAAAAAAAA 70915 ||||||||||||||||| |||||||||||||||||||||||||||||||||||||||||| Old 70857 TTATTTTTTTTTTGTTAAAATTGATCCAAATGTAAATAAACAATCACAAGGAAAAAAAAA 70916 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	ARS104, YAL063C	28953	28953	Insertion		T
		28069	28069	Deletion	T
	A single nucleotide deletion and a single nucleotide insertion were made in the intergenic region between ORF FLO9/YAL063C and ARS104. New 28027 GTAAATAAGAAGGAAGAACGTTATGTTATTAATGGACTTTT-AGTGTCATCGAATTTTAT 28085 ||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||| Old 28028 GTAAATAAGAAGGAAGAACGTTATGTTATTAATGGACTTTTTAGTGTCATCGAATTTTAT 28087 New 28916 AGTAAACAAGAGATACCTAATTTCACAGCCACTTTTTGTTGCGGACACTGACGGGATGTG 28975 |||||||||||||||||||||||||||||||||||| ||||||||||||||||||||||| Old 28918 AGTAAACAAGAGATACCTAATTTCACAGCCACTTTT-GTTGCGGACACTGACGGGATGTG 28976 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAR023C, tL(CAA)A	180961	180961	Insertion		CAAA
	A tetranucleotide insertion was made in the intergenic region between ORF YAR023C and tRNA-Leu SUP56/tL(CAA)A. New 180942 TTCCCATTACAATGCCGAATAGCAAAATATGTAGTAGAACACGTACACGCATGATAATTA 181001 |||||||||||||||||||||| |||||||||||||||||||||||||||||||||| Old 180940 TTCCCATTACAATGCCGAATAG----ATATGTAGTAGAACACGTACACGCATGATAATTA 180995 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAL041W, YAL042W	62767	62767	Substitution	A	G
	A single nucleotide substitution was made in the intergenic region between ORFs ERV46/YAL042W and CDC24/YAL041W. New 62756 TAGGATAGCAGAAGAGTACCATTGCTGTTATCATTTGTTGCCTAGCCCTATCAAGACCTG 62815 |||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||| Old 62757 TAGGATAGCAAAAGAGTACCATTGCTGTTATCATTTGTTGCCTAGCCCTATCAAGACCTG 62816 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAR047C, YAR050W	203327	203327	Insertion		T
		202933	202933	Insertion		A
	Two separate single nucleotide insertions were made in the intergenic region between ORFs YAR047C and FLO1/YAR050W. New 202902 GCTCATTAATTGCCCTCACAAGAATTTGGAAGTGCGTAGAACAGGTAAAAGATTGTACTA 202961 ||||||||||||||||||||||||||||||||||||||| |||||||||||||||||||| Old 202895 GCTCATTAATTGCCCTCACAAGAATTTGGAAGTGCGTAG-ACAGGTAAAAGATTGTACTA 202953 New 203322 TTCACTCTTGCTCGTTTGATGTAAGCTCTCTTCCGGGTTCTTATTTTTAATTCTTGTCAC 203381 |||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||| Old 203314 TTCACTCTTGCTCG-TTGATGTAAGCTCTCTTCCGGGTTCTTATTTTTAATTCTTGTCAC 203372 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAR042W, YAR047C	198900	198900	Insertion		A
	A single nucleotide insertion was made in the intergenic region between ORFs SWH1/YAR042W and YAR047C. New 198882 TAAGCCCCTTTTATGGATGCATGAGAAAAAAAAAAAGGTTTGCTACAACCATCTCAGGTC 198941 ||||||||||||||||||||||||| |||||||||||||||||||||||||||||||||| Old 198876 TAAGCCCCTTTTATGGATGCATGAG-AAAAAAAAAAGGTTTGCTACAACCATCTCAGGTC 198934 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAR020C, YAR023C	178647	178647	Substitution	T	C
		178638	178638	Deletion	G
		178618	178618	Insertion		A
		178601	178601	Deletion	A
		178256	178256	Substitution	G	C
		177135	177135	Insertion		T
	Several nucleotide sequence changes were made in the intergenic region between ORFs PAU7/YAR020C and YAR023C. New 177104 CAAAGCTGATCAAGCCGCTGTATTTATATGAAACTTTGAACAACTACATCTGCACACATG 177163 |||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||| Old 177102 CAAAGCTGATCAAGCCGCTGTATTTATATGAAAC-TTGAACAACTACATCTGCACACATG 177160 New 178244 ACAATTTAACCATGGCAGGTTAAAATATTACTGCGATCAGTAAAAATGGGGATATCACCT 178303 ||||||||||||||| |||||||||||||||||||||||||||||||||||||||||||| Old 178241 ACAATTTAACCATGGGAGGTTAAAATATTACTGCGATCAGTAAAAATGGGGATATCACCT 178300 New 178599 ATTGT-AGATTGTATCGTTCGAGAAACGTCAGGCATGATAGAT-GTTGCAATCACAGGAC 178656 ||||| ||||||||||||||||| ||||||||||||||||||| |||||||| ||||||| Old 178596 ATTGTAAGATTGTATCGTTCGAG-AACGTCAGGCATGATAGATGGTTGCAATTACAGGAC 178654 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAR018C, YAR019C	172170	172170	Insertion		T
		172042	172042	Insertion		T
		172041	172041	Insertion		T
		172020	172020	Deletion	A
		172018	172018	Deletion	A
		171983	171983	Deletion	G
		171975	171977	Deletion	CTA
		171972	171972	Substitution	C	T
		171968	171968	Deletion	C
		171882	171882	Insertion		C
	Several nucleotide sequence changes were made in the intergenic region between ORFs KIN3/YAR018C and CDC15/YAR019C. New 171843 GTAATGAAAAAATTCAGAAACCTTAAAAAAAAAACTTGGCTGTAACCTATCGGAAGACTG 171902 ||||||||||||||||||||||||||||||||||||||||||||| |||||||||||||| Old 171838 GTAATGAAAAAATTCAGAAACCTTAAAAAAAAAACTTGGCTGTAA-CTATCGGAAGACTG 171896 New 171953 CTAGAAACATTTAACAAAATG-CACTTT---GAGTC-GTTCATACATTTAATCCCCAATT 172007 ||||||||||||||||||||| ||| || ||||| ||||||||||||||||||||||| Old 171947 CTAGAAACATTTAACAAAATGCCACCTTCTAGAGTCGGTTCATACATTTAATCCCCAATT 172006 New 172008 GAAAAAAAAAA-G-AAAAGAAAAAAAGCATATATATGTATATGCTTTTTTATCATTACTG 172065 ||||||||||| | ||||||||||||||||||||| | |||||||||||||||||||||| Old 172007 GAAAAAAAAAAAGAAAAAGAAAAAAAGCATATATA-G-ATATGCTTTTTTATCATTACTG 172064 New 172126 GGAAGGTTCACAATTCTATATATAGTGTTAATGTAATGCTGTATTATTTCTCTATATATG 172185 |||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||| Old 172125 GGAAGGTTCACAATTCTATATATAGTGTTAATGTAATGCTGTATTA-TTCTCTATATATG 172183 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAR007C, YAR008W	158934	158934	Insertion		G
	A single nucleotide insertion was made in the intergenic region between ORFs RFA1/YAR007C and SEN34/YAR008W. New 158923 TAACATATATGCAAAAAGAACGGCAAAAGGCGAGGAGGTTTTTATGCCACCGCTAGTATT 158982 |||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||| Old 158925 TAACATATAT-CAAAAAGAACGGCAAAAGGCGAGGAGGTTTTTATGCCACCGCTAGTATT 158983 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	CEN1, YAR002W	152189	152190	Substitution	CA	AC
	A dinucleotide substitution was made in the intergenic region between CEN1 and ORF NUP60/YAR002W New 152153 ATATATTTACAAGTGAAAGCTTATTGTAATGTGTACTTTTAAACATCAAATAACAGACCT 152212 |||||||||||||||||||||||||||||||||| |||||||||||||||||||||||| Old 152155 ATATATTTACAAGTGAAAGCTTATTGTAATGTGTCATTTTAAACATCAAATAACAGACCT 152214 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAL067C, YAL067W-A	6454	6454	Deletion	C
		5927	5927	Insertion		G
		5244	5244	Substitution	G	A
		3981	3982	Substitution	AT	TA
		3836	3836	Deletion	C
	Several nucleotide sequence changes were made in the intergenic region between ORFs YAL067W-A and SEO1/YAL067C. New 3791 CTTGGTAGTAACCATAATATTACCCAGGTACGAAACGCTAAGAAC-TTGAAAGACTCATA 3849 ||||||||||||||||||||||||||||||||||||||||||||| |||||||||||||| Old 3791 CTTGGTAGTAACCATAATATTACCCAGGTACGAAACGCTAAGAACCTTGAAAGACTCATA 3850 New 3960 TTTCCATTTTGATAATGAGCTAGTGATCCGGAAAGCTACTTTATGATGTTTCAAGGCCTG 4019 |||||||||||||||||||| |||||||||||||||||||||||||||||||||||||| Old 3961 TTTCCATTTTGATAATGAGCATGTGATCCGGAAAGCTACTTTATGATGTTTCAAGGCCTG 4020 New 5220 TAAATAGTTTTCAACTGCTGGTGATAAATCAATAATTTATGTTCTTAACCTAACATTTGA 5279 ||||||||||||||||||||||| |||||||||||||||||||||||||||||||||||| Old 5221 TAAATAGTTTTCAACTGCTGGTGGTAAATCAATAATTTATGTTCTTAACCTAACATTTGA 5280 New 5880 AACTGCATTCGGACTATGAAAGAAAAAATGGTAGTAGCAAAGGATAGGCATCGCCGTATT 5939 ||||||||||||||||||||||||||||||||||||||||||||||| |||||||||||| Old 5881 AACTGCATTCGGACTATGAAAGAAAAAATGGTAGTAGCAAAGGATAG-CATCGCCGTATT 5939 New 6420 AAGTTTCTTAAATAACCCGGATTGGTTAGGTTCA-GCCATGCCTGGCGCGTACATTGAGG 6478 |||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||| Old 6420 AAGTTTCTTAAATAACCCGGATTGGTTAGGTTCACGCCATGCCTGGCGCGTACATTGAGG 6479 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAL064C-A, YAL064W	16500	16500	Deletion	G
		16470	16470	Deletion	T
		16457	16457	Substitution	G	A
	A single nucleotide substitution and two separate single nucleotide deletions were made in the intergenic region between ORFs YAL064C-A and YAL064W. New 16449 TCTGTGGAAAATAAGAAATT-CAGCACCAGTAAAAGACGAGAAATATAGG-CACATAAAT 16506 ||||||| |||||||||||| ||||||||||||||||||||||||||||| ||||||||| Old 16450 TCTGTGGGAAATAAGAAATTTCAGCACCAGTAAAAGACGAGAAATATAGGGCACATAAAT 16509 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAL063C, YAL063C-A	23253	23253	Insertion		T
	A single nucleotide insertion was made in the intergenic region between ORFs YAL063C-A and FLO9/YAL063C. New 23217 TTTGCTCATCATTGGATAATTTCTTTTTTTTTTTTTGATGCATCCAAACTTGGACCCCTT 23276 ||||||||||||||||||||||||||||||||||| |||||||||||||||||||||||| Old 23219 TTTGCTCATCATTGGATAATTTCTTTTTTTTTTTT-GATGCATCCAAACTTGGACCCCTT 23277 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAL021C, YAL022C	110470	110471	Substitution	CG	GC
	A dinucleotide substitution was made in the intergenic region between ORFs FUN26/YAL022C and CCR4/YAL021C. New 110455 GCGTTTGATGATAAGCTGTCGCCGTAACGTAAATCATTCATCCTTTCCTATGATTTTTTA 110514 |||||||||||||| |||||||||||||||||||||||||||||||||||||||||||| Old 110456 GCGTTTGATGATAACGTGTCGCCGTAACGTAAATCATTCATCCTTTCCTATGATTTTTTA 110515 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	YAL010C, YAL011W	134125	134125	Insertion		C
	A single nucleotide substitution was made in the intergenic region between ORFs SWC3/YAL011W and MDM10/YAL010C. New 134093 ATTCTGCTTTAACGCCATTATGATTATACACATTGTATTACTTATTTTTTAACCTGTATA 134152 |||||||||||||||||||||||||||||| ||||||||||||||||||||||||||||| Old 134096 ATTCTGCTTTAACGCCATTATGATTATACA-ATTGTATTACTTATTTTTTAACCTGTATA 134154 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2011-02-03	TEL01R TEL01R-XC	229568	229568	Insertion		G
	A single nucleotide insertion was made within the right telomere of Chromosome 1, TEL01R specifically within the X element Core sequence TEL01R-XC. New 229542 ATTACGCATGGAGTTAAGAGTATTTACATGATAATTGGGGTTCCGTGATTCATTATAGAT 229601 |||||||||||||||||||||||||||||||||||| ||||||||||||||||||||||| Old 229533 ATTACGCATGGAGTTAAGAGTATTTACATGATAATT-GGGTTCCGTGATTCATTATAGAT 229591 Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
2008-03-05	YAL044C	58424	58424	Substitution	C	T
		58247	58247	Substitution	A	C
		58196	58196	Substitution	A	C
	Three single base substitutions were made within ORF YAL044C/GCV3 to correct errors in the systematic reference sequence for Chromosome I: Two separate A -> C transversions at 58196 and 58247, and a C -> T transition at 58424. These errors were verified by sequencing in 3 different strains, all of ResGen BY4741 (S288C) background. SGD thanks Michael E. Rice for bringing these errors to our attention, and for verifying the correct sequence. New: 58191 TTGGGCAATCTCAGTGCCCACTTCTGGCAACTCAACATAGGTAGCGTCCCCTAAGGCATC 58250 ||||| |||||||||||||||||||||||||||||||||||||||||||||||||| ||| Old: 58191 TTGGGAAATCTCAGTGCCCACTTCTGGCAACTCAACATAGGTAGCGTCCCCTAAGGAATC 58250 New: 58251 AGTGGCGTATTTTGTAATTCCGACAAAGGCAGTCTTGTCCTGATGCACAGCTATCCACTC 58310 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| Old: 58251 AGTGGCGTATTTTGTAATTCCGACAAAGGCAGTCTTGTCCTGATGCACAGCTATCCACTC 58310 New: 58311 ATGTTGGGAAGTGTACCTCACGGCTTGAGGTCCTTGGGATGAGTACAAAAATGGTAGTTT 58370 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| Old: 58311 ATGTTGGGAAGTGTACCTCACGGCTTGAGGTCCTTGGGATGAGTACAAAAATGGTAGTTT 58370 New: 58371 ATTCTTGTTTAGGGCATTGCCGGAGCTGTTTCTCAAAAACAATTTGCTCACAGTGGGCAT 58430 ||||||||||||||||||||||||||||||||||||||||||||||||||||| |||||| Old: 58371 ATTCTTGTTTAGGGCATTGCCGGAGCTGTTTCTCAAAAACAATTTGCTCACAGCGGGCAT 58430
2007-04-05	YAL004W, YAL005C	140169	140169	Substitution	A	G
		140182	140182	Substitution	A	G
		140811	140811	Substitution	A	G
	Three single nucleotide substitutions were made within the coding sequence of SSA1 (at nucleotide positions 623, 1252, and 1265 relative to the SSA1 coding sequence), based on the sequence reported by Slater and Craig (1989) and corresponding to GenBank entry X12926. These changes result in phenylalanine to serine changes at amino acid residues 208 and 422 and a change from serine to proline at amino acid residue 418. Thanks to Andreas Bracher for bringing these corrections to our attention. Note that the change at position 623 of SSA1 also affects the coding sequence of the Dubious ORF YAL004W. 638 ATACCGTCTTCAATGGACAACAAAGAGAC 610 new sequence, coordinates relative to SSA1 coding region ||||||||||||||| ||||||||||||| |- | || ||140796 ATACCGTCTTCAATGAACAACAAAGAGAC 140824 old sequence, chromosomal coordinates |- | || ||1279 TGGAAAAGATCTCGGACTTCTTTGTTGGAATGGTAGAGTTT 1239 new sequence, coordinates relative to SSA1 coding region |||||||||||||| |||||||||||| ||||||||||||| |- | || ||140155 TGGAAAAGATCTCGAACTTCTTTGTTGAAATGGTAGAGTTT 140195 old sequence, chromosomal coordinates Slater MR and Craig EA (1989) The SSA1 and SSA2 genes of the yeast Saccharomyces cerevisiae. Nucleic Acids Res 17(2):805-6
2006-01-19	YAR042W	193355	193355	Substitution	G	A
	When confirming the G nucleotide insertion that resulted in the merger of SWH1/YAR042W and OSH1/YAR044W (see 2003-09-27), SGD detected an additional sequencing error. The substitution of an A nt for a G nt changes amino acid 248 from a serine to an asparagine. Substitute an A nt for the G nt at 193355 New: 193341 CGACACCGCCACCAACACCAAGATCGCCATC 193371 |||||||||||||| |||||||||||||||| Old: 193341 CGACACCGCCACCAGCACCAAGATCGCCATC 193371
2004-07-20	YAL051W	51694	51694	Deletion	G
		51688	51688	Deletion	G
	The work of Kellis et al. 2003 predicted the deletion of 2 separate G nucleotides in YAL051W at chromosomal coordinates 51688 and 51694, and these sequence errors were confirmed in S288C by SGD. As a consequence of these changes, YAL051W was shortened at the 3' end, altering the C-terminus and decreasing the size of the predicted protein from 1062 to 1047 amino acids. New: 51666 TTTATTTGATTATGACTTTTTG-TTTGG-CAATGACTTTGCTTAAAAATTTTCTTTCCAA 51723 |||||||||||||||||||||| ||||| ||||||||||||||||||||||||||||||| Old: 51666 TTTATTTGATTATGACTTTTTGGTTTGGGCAATGACTTTGCTTAAAAATTTTCTTTCCAA 51725 Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54
2004-01-30	YAR014C	166772	166772	Deletion	G
	Kellis et al. 2003 predicted and confirmed the deletion of a single G nucleotide at chromosomal coordinate 166772. As a consequence of this sequence change, YAR014C was extended at the 3' end, altering the C-terminus and increasing the size of the predicted protein from 702 to 707 amino acids. New: 166731 TTGTAAGGACAATATCATTTACGAATAATTTCATCCAATTG-TTTCATCAACACA 166784 ||||||||||||||||||||||||||||||||||||||||| ||||||||||||| Old: 166731 TTGTAAGGACAATATCATTTACGAATAATTTCATCCAATTGGTTTCATCAACACA 166785 Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54
2004-01-24	YAL056W	41778	41778	Insertion		G
	Kellis et al. 2003 predicted and confirmed the insertion of a single G nucleotide after the T at chromosomal coordinate 41778. As a consequence of this sequence change, YAL056W was extended at the 3' end, altering the C-terminus and increasing the size of the predicted protein increasing from 847 to 880 amino acids. New: 41724 GCGAAAATGAAGATACAAATTCAAATATAGTAGTTGGTGTCGGTGGCACTTCTTTGCAAT 41783 ||||||||||||||||||||||||||||||||||||||||||||||||||||||| |||| Old: 41724 GCGAAAATGAAGATACAAATTCAAATATAGTAGTTGGTGTCGGTGGCACTTCTTT-CAAT 41782 Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54
2004-01-22	YAL002W	143848	143848	Insertion		C
	Kellis et al. 2003 and Cliften et al. 2003 predicted and confirmed the insertion of a single C nucleotide after the C at chromosomal coordinate 143848. As a consequence of this sequence change, YAL002W was extended at the 5' end, altering the N-terminus and increasing the size of the predicted protein from 1176 to 1274 amino acids. New: 143826 ATCTAGTTCTTCATATACGGCACCTCCCCTGAACGAAGATGGTCCTAAAGGGGTAGCTTC 143885 ||||||||||||||||||||||| |||||||||||||||||||||||||||||||||||| Old: 143826 ATCTAGTTCTTCATATACGGCAC-TCCCCTGAACGAAGATGGTCCTAAAGGGGTAGCTTC 143884 Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54 Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6
2003-12-17	YAL013W	130239	130239	Insertion		C
		130246	130247	Substitution	CG	GC
	Kellis et al. 2003 and Brachat et al. 2003 predicted and confirmed the insertion of a single C nucleotide after the C at position 130239 on Chromosome I. As a consequence of this sequence change, YAL013W was extended at the 3' end, altering the C-terminus and increasing the size of the predicted protein from 362 to 420 amino acids. They also found an additional seqeuncing error: the CG at 130246-130247 should be GC. Old: 130201 ACTTGATAACAAGACGCTGAGCTGTATCACGGGCTACGC-AGCGCACGACAGCTGTGCTA 130259 ||||||||||||||||||||||||||||||||||||||| |||||| |||||||||||| New: 130201 ACTTGATAACAAGACGCTGAGCTGTATCACGGGCTACGCCAGCGCAGCACAGCTGTGCTA 130260 Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54 Brachat S, et al. (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45
2003-09-27	YAR042W, YAR044W	193300	193300	Insertion		G
	Insertion of a single G after the G at 193300 merged SWH1/YAR042W and OSH1/YAR044W. After merging YAR042W (coordinates 192613-193383 (1-771)) and YAR044W (coordinates 193599-196178 (1-2580)), the coordinates of the merged ORF, SWH1/YAR042W, are 192613-196179 (1-3567). OSH1 and YAR044W are now aliases of SWH1/YAR042W. This sequence change was predicted by several studies, then verified in S288c by SGD. Old: 193261 CTTGAACACGGTGCTGACCCCTTCAAGAGAGACCGCAAGG-CAAACTGCCCATCGAGCTC 193319 |||||||||||||||||||||||||||||||||||||||| ||||||||||||||||||| New: 193261 CTTGAACACGGTGCTGACCCCTTCAAGAGAGACCGCAAGGGCAAACTGCCCATCGAGCTC 193320 Schmalix WA and Bandlow W (1994) SWH1 from yeast encodes a candidate nuclear factor containing ankyrin repeats and showing homology to mammalian oxysterol-binding protein. Biochim Biophys Acta 1219(1):205-10 Beh CT, et al. (2001) Overlapping functions of the yeast oxysterol-binding protein homologues. Genetics 157(3):1117-40 Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54 Brachat S, et al. (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45 Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6
2002-12-17	YAL023C	108137	108137	Insertion		CC
		108143	108143	Insertion		G
	Due to the insertion of CC after the C at 108137, and the insertion of a G after the G at 108143 in the systematic sequence of Chromosome I, the coordinates of PMT2/YAL023C have been changed. Thanks to Verena Girrbach (verena.girrbach@biologie.uni-regensburg.de) for reporting this sequence error in the systematic sequence of PMT2/FUN25/YAL023C to SGD. Old: 108121 AGTCTGGGTAAATTTCC--AGAAGG-AAGTCCCAAGAACCGTTGTAGCCTGCCAAATAAC 108177 ||||||||||||||||| |||||| |||||||||||||||||||||||||||||||||| New: 108121 AGTCTGGGTAAATTTCCCCAGAAGGGAAGTCCCAAGAACCGTTGTAGCCTGCCAAATAAC 108180
2002-12-17	YAL014C	128441	128441	Insertion		T
	Due to the insertion of a single T nucleotide after the T at coordinate 128441 in the systematic sequence of Chromosome I, the ORF SUN8/YAL014C was extended 450 nucleotides in the 3' direction, making the protein product 150 amino acids longer at the C-terminus. Thanks to Lena Burri, Trevor Lithgow, and Hugh Pelham for reporting this sequence error in the systematic sequence of SYN8/UIP2/YAL014C to SGD. Old: 128398 TTCTAAATCAACCAGCAGCGAGTCGTTCTGAGAAACGATCTCAT-ATTAAGGTCCAGCGA 128456 |||||||||||||||||||||||||||||||||||||||||||| ||||||||||||||| New: 128401 TTCTAAATCAACCAGCAGCGAGTCGTTCTGAGAAACGATCTCATTATTAAGGTCCAGCGA 128460 Lewis MJ and Pelham HR (2002) A new yeast endosomal SNARE related to mammalian syntaxin 8. Traffic 3(12):922-9
1998-09-02	YAL062W, YAL063C	29254	29254	Deletion	A
		29289	29289	Deletion	A
		29290	29290	Deletion	A
		29291	29291	Deletion	T
		29307	29307	Deletion	A
		29301	29301	Substitution	T	A
	The following changes were made to the systematic sequence of Chromosome I in the region encompassing features FLO9/YAL063C and GDH3/YAL062W: deletion of the A at 29254, deletion of AAT at 29289-29291, transversion of T to A at 29301, and deletion of the A at 29307. Old: 29221 TGAAATCATACCTGCCAAGCTTGCTGCACTTGGAAAGGCAACTCCGTTTTTCAGAGATTA 29280 ||||||||||||||||||||||||||||||||||| |||||||||||||||||||||||| New: 29221 TGAAATCATACCTGCCAAGCTTGCTGCACTTGGAA-GGCAACTCCGTTTTTCAGAGATTA 29279 Old: 29281 GATCCTTTAATTTTTTTTGATGAAAAAGGCAGCCAAGTTACGTCATAGAGAAAACTCCCT 29340 |||||||| ||||||||| ||||| ||||||||||||||||||||||||||||||||| New: 29280 GATCCTTT---TTTTTTTGAAGAAAA-GGCAGCCAAGTTACGTCATAGAGAAAACTCCCT 29335
1998-09-02	YAR060C, YARCdelta8	210810	210810	Substitution	T	A
		211011	211011	Substitution	C	T
		210804	210804	Deletion	T
	The following changes were made to the systematic sequence of Chromosome I in the region encompassing features YARCdelta8 and YAR060C: deletion of the T at 210804, transversion of T to A at 210810, and transition of C to T at 211011. Old: 210781 TTTCTCTTTGCTTGCATCTTTTTTCTTCCTTGCCAAAAAATAAAAGATACTCATTTTAAA 210840 ||||||||||||||||||||||| ||||| |||||||||||||||||||||||||||||| New: 210776 TTTCTCTTTGCTTGCATCTTTTT-CTTCCATGCCAAAAAATAAAAGATACTCATTTTAAA 210834 Old: 210961 GCCCTTCTACGGCTTCTTCTAACCAATTGTTCCCCGTGAGTTGCTTTCTCCGAAAACCTT 211020 |||||||||||||||||||||||||||||||||||||||||||||||||| ||||||||| New: 210955 GCCCTTCTACGGCTTCTTCTAACCAATTGTTCCCCGTGAGTTGCTTTCTCTGAAAACCTT 211014
1998-09-02	YAR050W	203939	203939	Substitution	T	G
	The following sequence change was made to the systematic sequence of Chromosome I within the ORF YAR050W/FLO1: transversion of T to G at 203939. Old: 203881 CAATTCTATCAGTAGGTGGTGCAACCGCGTTCAACTGTTGTGCTCAACAGCAACCGCCTA 203940 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||| | New: 203876 CAATTCTATCAGTAGGTGGTGCAACCGCGTTCAACTGTTGTGCTCAACAGCAACCGCCGA 203935