Positions in yeast labs

Systems Chemical Biologist at Yumanity Therapeutics (posted 7 December 2018)

Description: Yumanity Therapeutics (http://www.yumanity.com/) is transforming drug discovery for neurodegenerative diseases caused by protein misfolding. Even though an estimated 50 million people worldwide suffer from diseases affecting the brain and central nervous system, there are no approved disease-modifying therapies or cures. Yumanity is working to identify and develop new, disease-modifying therapies that address illnesses such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis (ALS). The company’s approach concentrates on correcting the cellular pathologies driven by misfolded proteins, the altered biology or phenotypes driving these diseases.

Position Overview: The systems chemical biologist will work as an integral part of the target identification team, which uses large-scale forward and reverse genetic approaches to reveal the cellular targets of compounds discovered from phenotypic screens. The position reports to the target identification team lead, and will interact across all Yumanity’s core platforms, including chemistry, yeast screening, and mammalian validation. The successful candidate will become a key individual contributor in a dynamic and multidisciplinary environment. They will demonstrate a respect for others and be highly effective in a team.

For more information on this position, please visit the Yumanity careers page (http://www.yumanity.com/careers/). If you would like to apply, please submit your CV with the "Systems Chemical Biologist" in the subject line to careers@yumanity.com.

Postdoctoral Researcher or Research Scientist Position (1 position) in the Boone Team (RIKEN, Japan) (posted 7 December 2018)

A Postdoctoral Researcher or Research Scientist position is available in Dr. Charles Boone’s laboratory at RIKEN (http://www.riken.jp/en/research/labs/csrs/mol_ligand_targ). We are seeking a highly motivated candidate with strong expertise in yeast genetics/molecular biology and human cell culture experiments. The candidate will develop innovative techniques based on genetic networks in yeast and human cells that leads to quick and accurate detection of the ligand-target interactions.

How to apply: Please check the website (http://www.riken.jp/en/careers/researchers/20181129_5/) for the details.

Postdoctoral Position in Yeast Molecular Biology (posted 5 September 2018)

A NIH-funded postdoctoral position is available in the laboratory of Dr. David Kadosh in the Department of Microbiology, Immunology & Molecular Genetics at the University of Texas Health Science Center at San Antonio. Research will use cutting-edge techniques to study molecular mechanisms that control gene expression, morphology, virulence and virulence-related properties in response to host environmental cues in the yeast Candida albicans, a major human fungal pathogen. For additional details and previous publications, please see https://wp.uthscsa.edu/mimg/team-member/david-kadosh-ph-d/.

Highly motivated individuals with previous experience and a strong track record in molecular biology, genomics, cell biology, genetics, bioinformatics and/or protein chemistry are especially encouraged to apply. Previous experience in fungal pathogenesis is not necessarily required. Please send a cover letter outlining your research interests, CV, and contact information for three references to David Kadosh (kadosh@uthscsa.edu).

Many opportunities are available for collaboration with both basic and clinical researchers at the large and internationally recognized San Antonio Center for Medical Mycology (see http://www.sacmm.org/).

The successful applicant will receive equivalent to NIH-level salary and full benefits. Located in south central Texas, near both Austin and the Texas Hill Country, San Antonio is one of the lowest cost-of-living major metropolitan areas in the U.S.

All postdoctoral appointments are designated as security sensitive positions. The University of Texas Health Science Center at San Antonio is an Equal Employment Opportunity/Affirmative Action Employer.

The Kupiec lab is recruiting PhD students and post-docs (posted 2 July 2018)

Description: PhD positions and post-doctoral research positions are available in Prof. Martin Kupiec’s laboratory at Tel Aviv University (https://mkyeastlab.wixsite.com/mklab). We work with yeast (S. cerevisiae and S. pombe) exploring the role of Elg1 and other proteins in genome stability maintenance and telomere biology. Additional projects include exploring the interphase between DNA replication, chromatin modifications, sister-chromatid cohesion and DNA repair.

We are seeking highly motivated candidates with expertise in molecular biology and genetics. Experience in yeast genetics is desirable, but not a requirement. Independence, communication and interpersonal skills are valued in order to work in a young, dynamic, diverse, and collaborative environment. We are an international team, and research is carried out in English.

How to apply: Prospective candidates should submit a cover letter describing their research experience, scientific interest, career goals, and motivation to apply for this position. Please include an updated CV and the contact information of at least two references. Questions should be directed to Prof. Martin Kupiec at martin@post.tau.ac.il.