YKL134C

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Systematic name YKL134C
Gene name OCT1
Aliases
Feature type ORF, Verified
Coordinates Chr XI:191441..189129


Description of YKL134C: Mitochondrial intermediate peptidase, cleaves N-terminal residues of a subset of proteins upon import, after their cleavage by mitochondrial processing peptidase (Mas1p-Mas2p); may contribute to mitochondrial iron homeostasis[1][2]




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References

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  1. Isaya G, et al. (1994) MIP1, a new yeast gene homologous to the rat mitochondrial intermediate peptidase gene, is required for oxidative metabolism in Saccharomyces cerevisiae. Mol Cell Biol 14(8):5603-16 SGD PMID 8035833
  2. Branda SS, et al. (1999) Mitochondrial intermediate peptidase and the yeast frataxin homolog together maintain mitochondrial iron homeostasis in Saccharomyces cerevisiae. Hum Mol Genet 8(6):1099-110 SGD PMID 10332043

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