YGR048W
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Systematic name | YGR048W |
Gene name | UFD1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr VII:589826..590911 |
Primary SGDID | S000003280 |
Description of YGR048W: Protein that interacts with Cdc48p and Npl4p, involved in recognition of polyubiquitinated proteins and their presentation to the 26S proteasome for degradation; involved in transporting proteins from the ER to the cytosol[1][2][3]
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Contents
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References
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- ↑ Bays NW and Hampton RY (2002) Cdc48-Ufd1-Npl4: stuck in the middle with Ub. Curr Biol 12(10):R366-71 SGD PMID 12015140
- ↑ Braun S, et al. (2002) Role of the ubiquitin-selective CDC48(UFD1/NPL4 )chaperone (segregase) in ERAD of OLE1 and other substrates. EMBO J 21(4):615-21 SGD PMID 11847109
- ↑ Ye Y, et al. (2001) The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol. Nature 414(6864):652-6 SGD PMID 11740563
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