YBR128C
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Systematic name | YBR128C |
Gene name | ATG14 |
Aliases | APG14, CVT12 |
Feature type | ORF, Verified |
Coordinates | Chr II:494109..493075 |
Description of YBR128C: Subunit of an autophagy-specific phosphatidylinositol 3-kinase complex (with Vps34p, Vps15p, and Vps30p) required for organization of a pre-autophagosomal structure; ATG14 transcription is activated by Gln3p during nitrogen starvation[1][2][3]
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References
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- ↑ Chan TF, et al. (2001) Regulation of APG14 expression by the GATA-type transcription factor Gln3p. J Biol Chem 276(9):6463-7 SGD PMID 11096087
- ↑ Kihara A, et al. (2001) Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae. J Cell Biol 152(3):519-30 SGD PMID 11157979
- ↑ Kametaka S, et al. (1998) Apg14p and Apg6/Vps30p form a protein complex essential for autophagy in the yeast, Saccharomyces cerevisiae. J Biol Chem 273(35):22284-91 SGD PMID 9712845
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