YPR180W
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Systematic name | YPR180W |
Gene name | AOS1 |
Aliases | RHC31 |
Feature type | ORF, Verified |
Coordinates | Chr XVI:895961..897004 |
Primary SGDID | S000006384 |
Description of YPR180W: Subunit of a heterodimeric nuclear SUMO activating enzyme (E1) with Uba2p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability[1][2]
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References
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- ↑ Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
- ↑ Johnson ES, et al. (1997) The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer. EMBO J 16(18):5509-19 SGD PMID 9312010
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