YPL096W

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Systematic name YPL096W
Gene name PNG1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:366927..368018
Primary SGDID S000006017


Description of YPL096W: Conserved peptide N-glycanase required for deglycosylation of misfolded glycoproteins during proteasome-dependent degradation; localizes to the cytoplasm and nucleus; activity is enhanced by interaction with Rad23p[1][2][3]




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References

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  1. Biswas S, et al. (2004) The N-terminus of yeast peptide: N-glycanase interacts with the DNA repair protein Rad23. Biochem Biophys Res Commun 323(1):149-55 SGD PMID 15351714
  2. Suzuki T, et al. (2000) PNG1, a yeast gene encoding a highly conserved peptide:N-glycanase. J Cell Biol 149(5):1039-52 SGD PMID 10831608
  3. Wang S, et al. (2009) N-terminal deletion of Peptide:N-glycanase results in enhanced deglycosylation activity. PLoS One 4(12):e8335 SGD PMID 20016784

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