YOR138C

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Systematic name YOR138C
Gene name RUP1
Aliases
Feature type ORF, Verified
Coordinates Chr XV:586324..584309
Primary SGDID S000005664


Description of YOR138C: Protein involved in regulation of Rsp5p, which is an essential HECT ubiquitin ligase; has a WW domain consensus motif of PPPSY (residues 131-135) that mediates binding of Rsp5p to Ubp2p; contains an UBA domain[1][2]




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References

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  1. Kee Y, et al. (2005) The Rsp5 ubiquitin ligase is coupled to and antagonized by the Ubp2 deubiquitinating enzyme. EMBO J 24(13):2414-24 SGD PMID 15933713
  2. Lam MH, et al. (2009) Interaction of the Deubiquitinating Enzyme Ubp2 and the E3 Ligase Rsp5 Is Required for Transporter/Receptor Sorting in the Multivesicular Body Pathway. PLoS ONE 4(1):e4259 SGD PMID 19165343

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