YDR183W

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Systematic name YDR183W
Gene name PLP1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:829585..830277
Primary SGDID S000002591


Description of YDR183W: Protein that interacts with CCT (chaperonin containing TCP-1) complex and has a role in actin and tubulin folding; has weak similarity to phosducins, which are G-protein regulators[1][2][3][4]




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References

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  1. Dekker C, et al. (2008) The interaction network of the chaperonin CCT. EMBO J 27(13):1827-39 SGD PMID 18511909
  2. Flanary PL, et al. (2000) Functional analysis of Plp1 and Plp2, two homologues of phosducin in yeast. J Biol Chem 275(24):18462-9 SGD PMID 10749875
  3. Lacefield S and Solomon F (2003) A novel step in beta-tubulin folding is important for heterodimer formation in Saccharomyces cerevisiae. Genetics 165(2):531-41 SGD PMID 14573467
  4. Stirling PC, et al. (2006) PhLP3 modulates CCT-mediated actin and tubulin folding via ternary complexes with substrates. J Biol Chem 281(11):7012-21 SGD PMID 16415341

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