YDR140W

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Systematic name YDR140W
Gene name MTQ2
Aliases
Feature type ORF, Verified
Coordinates Chr IV:734138..734803
Primary SGDID S000002547


Description of YDR140W: S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; subunit of complex with Trm112p that methylates translation release factor Sup45p (eRF1) in the ternary complex eRF1-eRF3-GTP; similar to E.coli PrmC[1][2][3][4]




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References

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  1. Heurgue-Hamard V, et al. (2005) The glutamine residue of the conserved GGQ motif in Saccharomyces cerevisiae release factor eRF1 is methylated by the product of the YDR140w gene. J Biol Chem 280(4):2439-45 SGD PMID 15509572
  2. Heurgue-Hamard V, et al. (2006) The Zinc Finger Protein Ynr046w Is Plurifunctional and a Component of the eRF1 Methyltransferase in Yeast. J Biol Chem 281(47):36140-8 SGD PMID 17008308
  3. Polevoda B, et al. (2006) The yeast translation release factors Mrf1p and Sup45p (eRF1) are methylated, respectively, by the methyltransferases Mtq1p and Mtq2p. J Biol Chem 281(5):2562-71 SGD PMID 16321977
  4. Studte P, et al. (2008) tRNA and protein methylase complexes mediate zymocin toxicity in yeast. Mol Microbiol 69(5):1266-77 SGD PMID 18657261

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