YDR017C

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Systematic name YDR017C
Gene name KCS1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:482267..479115
Primary SGDID S000002424


Description of YDR017C: Inositol hexakisphosphate (IP6) and inositol heptakisphosphate (IP7) kinase; generation of high energy inositol pyrophosphates by Kcs1p is required for many processes such as vacuolar biogenesis, stress response and telomere maintenance[1][2][3][4]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in phosphorus limited chemostat cultures versus phosphorus excess. [5] [6]




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References

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  1. ↑ Bennett M, et al. (2006) Inositol pyrophosphates: metabolism and signaling. Cell Mol Life Sci 63(5):552-64 SGD PMID 16429326
  2. ↑ Dubois E, et al. (2002) In Saccharomyces cerevisiae, the inositol polyphosphate kinase activity of Kcs1p is required for resistance to salt stress, cell wall integrity, and vacuolar morphogenesis. J Biol Chem 277(26):23755-63 SGD PMID 11956213
  3. ↑ Mulugu S, et al. (2007) A conserved family of enzymes that phosphorylate inositol hexakisphosphate. Science 316(5821):106-9 SGD PMID 17412958
  4. ↑ Saiardi A, et al. (2000) The inositol hexakisphosphate kinase family. Catalytic flexibility and function in yeast vacuole biogenesis. J Biol Chem 275(32):24686-92 SGD PMID 10827188
  5. ↑ Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  6. ↑ submitted by Viktor Boer on 2003-07-25

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