YKR071C
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Systematic name | YKR071C |
Gene name | DRE2 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XI:575980..574934 |
Primary SGDID | S000001779 |
Description of YKR071C: Conserved component of an early step in the cytosolic Fe-S protein assembly (CIA) machinery; contains an Fe-S cluster that receives electrons from NADPH via the action of Tah18p; ortholog of human Ciapin1[1][2][3]
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References
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- ↑ Netz DJ, et al. (2010) Tah18 transfers electrons to Dre2 in cytosolic iron-sulfur protein biogenesis. Nat Chem Biol 6(10):758-65 SGD PMID 20802492
- ↑ Vernis L, et al. (2009) A newly identified essential complex, Dre2-Tah18, controls mitochondria integrity and cell death after oxidative stress in yeast. PLoS ONE 4(2):e4376 SGD PMID 19194512
- ↑ Zhang Y, et al. (2008) Dre2, a conserved eukaryotic fe/s cluster protein, functions in cytosolic fe/s protein biogenesis. Mol Cell Biol 28(18):5569-82 SGD PMID 18625724
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