YPR133C

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Systematic name YPR133C
Gene name SPN1
Aliases IWS1
Feature type ORF, Verified
Coordinates Chr XVI:797206..795974
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Description of YPR133C: Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II, probable transcriptional elongation factor; metazoan homologs contain an acidic N terminus; mutations in the gene confer an Spt- phenotype[1][2]



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References

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  1. Lindstrom DL, et al. (2003) Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins. Mol Cell Biol 23(4):1368-78 SGD PMID 12556496
  2. Krogan NJ, et al. (2002) RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach. Mol Cell Biol 22(20):6979-92 SGD PMID 12242279

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