YPR041W

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Systematic name YPR041W
Gene name TIF5
Aliases SUI5
Feature type ORF, Verified
Coordinates Chr XVI:648701..649918
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Description of YPR041W: Translation initiation factor eIF-5; N-terminal domain functions as a GTPase-activating protein to mediate hydrolysis of ribosome-bound GTP; C-terminal domain is the core of ribosomal preinitiation complex formation[1][2]



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References

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  1. Asano K, et al. (2000) A multifactor complex of eukaryotic initiation factors, eIF1, eIF2, eIF3, eIF5, and initiator tRNA(Met) is an important translation initiation intermediate in vivo. Genes Dev 14(19):2534-46 SGD PMID 11018020
  2. Das S, et al. (2001) Eukaryotic translation initiation factor 5 functions as a GTPase-activating protein. J Biol Chem 276(9):6720-6 SGD PMID 11092890

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