YPL006W
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| Systematic name | YPL006W | |
| Gene name | NCR1 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr XVI:544628..548140 | |
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Description of YPL006W: Vacuolar membrane protein that transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; glycoprotein and functional orthologue of human Niemann Pick C1 (NPC1) protein[1][2]
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References
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- ↑ Zhang S, et al. (2004) Ncr1p, the yeast ortholog of mammalian Niemann Pick C1 protein, is dispensable for endocytic transport. Traffic 5(12):1017-30 SGD PMID 15522102
- ↑ Malathi K, et al. (2004) Mutagenesis of the putative sterol-sensing domain of yeast Niemann Pick C-related protein reveals a primordial role in subcellular sphingolipid distribution. J Cell Biol 164(4):547-56 SGD PMID 14970192
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