YOR226C
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| Systematic name | YOR226C | |
| Gene name | ISU2 | |
| Aliases | NUA2 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr XV:762085..761615 | |
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Description of YOR226C: Conserved protein of the mitochondrial matrix, required for synthesis of mitochondrial and cytosolic iron-sulfur proteins, performs a scaffolding function in mitochondria during Fe/S cluster assembly; isu1 isu2 double mutant is inviable[1][2][3]
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References
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- ↑ Gerber J, et al. (2004) The yeast scaffold proteins Isu1p and Isu2p are required inside mitochondria for maturation of cytosolic Fe/S proteins. Mol Cell Biol 24(11):4848-57 SGD PMID 15143178
- ↑ Schilke B, et al. (1999) Evidence for a conserved system for iron metabolism in the mitochondria of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 96(18):10206-11 SGD PMID 10468587
- ↑ Garland SA, et al. (1999) Saccharomyces cerevisiae ISU1 and ISU2: members of a well-conserved gene family for iron-sulfur cluster assembly. J Mol Biol 294(4):897-907 SGD PMID 10588895
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