YOR018W

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Systematic name YOR018W
Gene name ROD1
Aliases
Feature type ORF, Verified
Coordinates Chr XV:364369..366882
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Description of YOR018W: Membrane protein; overexpression confers resistance to the GST substrate o-dinitrobenzene as well as to zinc and calcium; contains 2 PY motifs, which are required for Rod1p interaction with Rsp5p, a hect-type ubiquitin ligase[1][2]



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References

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  1. Andoh T, et al. (2002) PY motifs of Rod1 are required for binding to Rsp5 and for drug resistance. FEBS Lett 525(1-3):131-4 SGD PMID 12163175
  2. Wu AL, et al. (1996) ROD1, a novel gene conferring multiple resistance phenotypes in Saccharomyces cerevisiae. J Biol Chem 271(6):2914-20 SGD PMID 8621680

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