YNR031C
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| Systematic name | YNR031C | |
| Gene name | SSK2 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr XIV:685435..680696 | |
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Description of YNR031C: MAP kinase kinase kinase of the HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress[1][2][3]
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References
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- ↑ Tatebayashi K, et al. (2003) A docking site determining specificity of Pbs2 MAPKK for Ssk2/Ssk22 MAPKKKs in the yeast HOG pathway. EMBO J 22(14):3624-34 SGD PMID 12853477
- ↑ Yuzyuk T, et al. (2002) The MEK kinase Ssk2p promotes actin cytoskeleton recovery after osmotic stress. Mol Biol Cell 13(8):2869-80 SGD PMID 12181352
- ↑ Posas F and Saito H (1998) Activation of the yeast SSK2 MAP kinase kinase kinase by the SSK1 two-component response regulator. EMBO J 17(5):1385-94 SGD PMID 9482735
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