YDL060W

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Systematic name YDL060W
Gene name TSR1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:341619..343985
Primary SGDID S000002218


Description of YDL060W: Protein required for processing of 20S pre-rRNA in the cytoplasm; associates with pre-40S ribosomal particles; inhibits the premature association of 60S subunits with assembling 40S subunits in the cytoplasm[1][2][3]




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References

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  1. Gelperin D, et al. (2001) Bms1p, a novel GTP-binding protein, and the related Tsr1p are required for distinct steps of 40S ribosome biogenesis in yeast. RNA 7(9):1268-83 SGD PMID 11565749
  2. Leger-Silvestre I, et al. (2004) The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeast. EMBO J 23(12):2336-47 SGD PMID 15167894
  3. Strunk BS, et al. (2011) Ribosome Assembly Factors Prevent Premature Translation Initiation by 40S Assembly Intermediates. Science () SGD PMID 21835981

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