YOL072W

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Systematic name YOL072W
Gene name THP1
Aliases BUD29
Feature type ORF, Verified
Coordinates Chr XV:194970..196337
Primary SGDID S000005433


Description of YOL072W: Nuclear pore-associated protein; forms a complex with Sac3p that is involved in transcription elongation and in mRNA export from the nucleus; contains a PAM domain implicated in protein-protein binding[1][2][3][4]




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References

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  1. Ciccarelli FD, et al. (2003) The PAM domain, a multi-protein complex-associated module with an all-alpha-helix fold. BMC Bioinformatics 4():64 SGD PMID 14687415
  2. Fischer T, et al. (2002) The mRNA export machinery requires the novel Sac3p-Thp1p complex to dock at the nucleoplasmic entrance of the nuclear pores. EMBO J 21(21):5843-52 SGD PMID 12411502
  3. Gallardo M, et al. (2003) Nab2p and the Thp1p-Sac3p complex functionally interact at the interface between transcription and mRNA metabolism. J Biol Chem 278(26):24225-32 SGD PMID 12702719
  4. Tous C, et al. (2011) A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors. EMBO J 30(10):1953-64 SGD PMID 21478823

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