YER022W
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| Systematic name | YER022W |
| Gene name | SRB4 |
| Aliases | MED17 |
| Feature type | ORF, Verified |
| Coordinates | Chr V:198812..200875 |
| Primary SGDID | S000000824 |
Description of YER022W: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; similar to the human MED17 gene[1][2][3]
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Contents
Community Commentary
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References
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- ↑ Kaufmann R, et al. (2010) Infantile Cerebral and Cerebellar Atrophy Is Associated with a Mutation in the MED17 Subunit of the Transcription Preinitiation Mediator Complex. Am J Hum Genet 87(5):667-70 SGD PMID 20950787
- ↑ Kornberg RD (2005) Mediator and the mechanism of transcriptional activation. Trends Biochem Sci 30(5):235-9 SGD PMID 15896740
- ↑ Thompson CM, et al. (1993) A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast. Cell 73(7):1361-75 SGD PMID 8324825
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