YNL008C

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Systematic name YNL008C
Gene name ASI3
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:618221..616212
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Description of YNL008C: Putative integral membrane E3 ubiquitin ligase; acts with Asi1p and Asi2p to ensure the fidelity of SPS-sensor signalling by maintaining the dormant repressed state of gene expression in the absence of inducing signals[1][2]



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References

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  1. Zargari A, et al. (2007) Inner nuclear membrane proteins asi1, asi2, and asi3 function in concert to maintain the latent properties of transcription factors stp1 and stp2. J Biol Chem 282(1):594-605 SGD PMID 17085444
  2. Forsberg H, et al. (2001) Suppressors of ssy1 and ptr3 null mutations define novel amino acid sensor-independent genes in Saccharomyces cerevisiae. Genetics 158(3):973-88 SGD PMID 11454748

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