YMR217W
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| Systematic name | YMR217W | |
| Gene name | GUA1 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr XIII:701789..703366 | |
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Description of YMR217W: GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation[1][2][3][4]
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References
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- ↑ Escobar-Henriques M, et al. (2003) Transcription initiation of the yeast IMD2 gene is abolished in response to nutrient limitation through a sequence in its coding region. Mol Cell Biol 23(17):6279-90 SGD PMID 12917348
- ↑ Gardner WJ and Woods RA (1979) Isolation and characterisation of guanine auxotrophs in Saccharomyces cerevisiae. Can J Microbiol 25(3):380-9 SGD PMID 222417
- ↑ Escobar-Henriques M and Daignan-Fornier B (2001) Transcriptional regulation of the yeast gmp synthesis pathway by its end products. J Biol Chem 276(2):1523-30 SGD PMID 11035032
- ↑ Dujardin G, et al. (1994) Cloning and sequencing of the GMP synthetase-encoding gene of Saccharomyces cerevisiae. Gene 139(1):127-32 SGD PMID 8112582
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