YMR116C
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| Systematic name | YMR116C | |
| Gene name | ASC1 | |
| Aliases | CPC2 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr XIII:500687..499455 | |
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Description of YMR116C: WD repeat protein (G-beta like protein) involved in translation regulation; required for repression of Gcn4p activity in the absence of amino-acid starvation; core component of the ribosome; ortholog of mammalian RACK1[1][2][3]
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References
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- ↑ Gerbasi VR, et al. (2004) Yeast Asc1p and mammalian RACK1 are functionally orthologous core 40S ribosomal proteins that repress gene expression. Mol Cell Biol 24(18):8276-87 SGD PMID 15340087
- ↑ Hoffmann B, et al. (1999) The WD protein Cpc2p is required for repression of Gcn4 protein activity in yeast in the absence of amino-acid starvation. Mol Microbiol 31(3):807-22 SGD PMID 10048025
- ↑ Chantrel Y, et al. (1998) The transcriptional regulator Hap1p (Cyp1p) is essential for anaerobic or heme-deficient growth of Saccharomyces cerevisiae: Genetic and molecular characterization of an extragenic suppressor that encodes a WD repeat protein. Genetics 148(2):559-69 SGD PMID 9504906
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