YLL015W

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Systematic name YLL015W
Gene name BPT1
Aliases
Feature type ORF, Verified
Coordinates Chr XII:116431..121110
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Description of YLL015W: ABC type transmembrane transporter of MRP/CFTR family, found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p[1][2][3]



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References

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  1. Klein M, et al. (2002) The ATP-binding cassette (ABC) transporter Bpt1p mediates vacuolar sequestration of glutathione conjugates in yeast. FEBS Lett 520(1-3):63-7 SGD PMID 12044871
  2. Bauer BE, et al. (1999) Inventory and function of yeast ABC proteins: about sex, stress, pleiotropic drug and heavy metal resistance. Biochim Biophys Acta 1461(2):217-36 SGD PMID 10581358
  3. Petrovic S, et al. (2000) The products of YCF1 and YLL015w (BPT1) cooperate for the ATP-dependent vacuolar transport of unconjugated bilirubin in Saccharomyces cerevisiae. Yeast 16(6):561-71 SGD PMID 10790694

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