YKL191W
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| Systematic name | YKL191W | |
| Gene name | DPH2 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr XI:81040..82644 | |
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Description of YKL191W: Protein required, along with Dph1p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph1p and Kti11p[1][2][3]
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References
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- ↑ Liu S, et al. (2004) Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2. Mol Cell Biol 24(21):9487-97 SGD PMID 15485916
- ↑ Fichtner L, et al. (2003) Elongator's toxin-target (TOT) function is nuclear localization sequence dependent and suppressed by post-translational modification. Mol Microbiol 49(5):1297-307 SGD PMID 12940988
- ↑ Mattheakis LC, et al. (1993) Diphthamide synthesis in Saccharomyces cerevisiae: structure of the DPH2 gene. Gene 132(1):149-54 SGD PMID 8406038
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