YDR293C
Share your knowledge...Edit this entry! <protect>
| Systematic name | YDR293C |
| Gene name | SSD1 |
| Aliases | CLA1, MCS1, RLT1, SRK1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1049392..1045640 |
| Primary SGDID | S000002701 |
Description of YDR293C: RNA-binding protein with a role in maintaining cellular integrity, interacts with TOR pathway components; transiently accumulates at sites of polarized growth; ssd1 mutant of a clinical S. cerevisiae strain displays elevated virulence[1][2][3][4][5]
</protect>
Community Commentary
About Community Commentary. Please share your knowledge!
Strain W303 has ssd1-d2 allele[6] in which the 2094th nucleotide C is substituted with G, resulting in a premature stop codon[7], whereas S288C and BY4741 strains have dominant SSD1-V[8], which encodes a full-length Ssd1 protein.
--S.hiraga 16:19, 29 April 2010 (UTC)
<protect>
References
See Help:References on how to add references
- ↑ Kaeberlein M and Guarente L (2002) Saccharomyces cerevisiae MPT5 and SSD1 function in parallel pathways to promote cell wall integrity. Genetics 160(1):83-95 SGD PMID 11805047
- ↑ Kurischko C, et al. (2011) The yeast Cbk1 kinase regulates mRNA localization via the mRNA-binding protein Ssd1. J Cell Biol 192(4):583-98 SGD PMID 21339329
- ↑ Ohyama Y, et al. (2010) Saccharomyces cerevisiae Ssd1p promotes CLN2 expression by binding to the 5'-untranslated region of CLN2 mRNA. Genes Cells 15(12):1169-88 SGD PMID 20977549
- ↑ Reinke A, et al. (2004) TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae. J Biol Chem 279(15):14752-62 SGD PMID 14736892
- ↑ Wheeler RT, et al. (2003) A Saccharomyces cerevisiae mutant with increased virulence. Proc Natl Acad Sci U S A 100(5):2766-70 SGD PMID 12589024
- ↑ Sutton et al. (1991) The SIT4 protein phosphatase functions in late G1 for progression into S phase. Mol Cell Biol 11(4):2133-48
- ↑ Jorgensen et al. (2002) High-Resolution Genetic Mapping With Ordered Arrays of Saccharomyces cerevisiae Deletion Mutants. Genetics 162(3):1091-9
- ↑ Sutton et al. (1991) The SIT4 protein phosphatase functions in late G1 for progression into S phase. Mol Cell Biol 11(4):2133-48
See Help:Categories on how to add the wiki page for this gene to a Category </protect> <protect>
References
See Help:References on how to add references
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
