YGL194C
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Systematic name | YGL194C | |
Gene name | HOS2 | |
Aliases | RTL1 | |
Feature type | ORF, Verified | |
Coordinates | Chr VII:141732..140374 | |
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Description of YGL194C: Histone deacetylase required for gene activation via specific deacetylation of lysines in H3 and H4 histone tails; subunit of the Set3 complex, a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity[1][2][3]
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References
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- ↑ Wang A, et al. (2002) Requirement of Hos2 histone deacetylase for gene activity in yeast. Science 298(5597):1412-4 SGD PMID 12434058
- ↑ Robyr D, et al. (2002) Microarray deacetylation maps determine genome-wide functions for yeast histone deacetylases. Cell 109(4):437-46 SGD PMID 12086601
- ↑ Pijnappel WW, et al. (2001) The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program. Genes Dev 15(22):2991-3004 SGD PMID 11711434
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