YGL043W
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| Systematic name | YGL043W | |
| Gene name | DST1 | |
| Aliases | PPR2 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr VII:417487..418416 | |
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Description of YGL043W: General transcription elongation factor TFIIS, enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites[1][2][3][4]
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References
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- ↑ Ubukata T, et al. (2003) Cleavage, but not read-through, stimulation activity is responsible for three biologic functions of transcription elongation factor S-II. J Biol Chem 278(10):8580-5 SGD PMID 12496271
- ↑ Olmsted VK, et al. (1998) Yeast transcript elongation factor (TFIIS), structure and function. I: NMR structural analysis of the minimal transcriptionally active region. J Biol Chem 273(35):22589-94 SGD PMID 9712887
- ↑ Wu J, et al. (1996) In vitro characterization of mutant yeast RNA polymerase II with reduced binding for elongation factor TFIIS. Proc Natl Acad Sci U S A 93(21):11552-7 SGD PMID 8876173
- ↑ Davie JK and Kane CM (2000) Genetic interactions between TFIIS and the Swi-Snf chromatin-remodeling complex. Mol Cell Biol 20(16):5960-73 SGD PMID 10913179
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