YFR025C
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| Systematic name | YFR025C | |
| Gene name | HIS2 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr VI:204738..203731 | |
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Description of YFR025C: Histidinolphosphatase, catalyzes the eighth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control[1][2]
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References
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- ↑ Alifano P, et al. (1996) Histidine biosynthetic pathway and genes: structure, regulation, and evolution. Microbiol Rev 60(1):44-69 SGD PMID 8852895
- ↑ Pearce DA and Sherman F (1999) Toxicity of copper, cobalt, and nickel salts is dependent on histidine metabolism in the yeast Saccharomyces cerevisiae. J Bacteriol 181(16):4774-9 SGD PMID 10438744
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