YHR100C
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| Systematic name | YHR100C |
| Gene name | GEP4 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:314676..314119 |
| Primary SGDID | S000001142 |
Description of YHR100C: Mitochondrial phosphatidylglycerophosphatase (PGP phosphatase), dephosphorylates phosphatidylglycerolphosphate to generate phosphatidylglycerol, an essential step during cardiolipin biosynthesis; null mutant is sensitive to tunicamycin, DTT[1][2]
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References
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- ↑ Osman C, et al. (2009) The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria. J Cell Biol 184(4):583-96 SGD PMID 19221197
- ↑ Osman C, et al. (2010) A mitochondrial phosphatase required for cardiolipin biosynthesis: the PGP phosphatase Gep4. EMBO J 29(12):1976-87 SGD PMID 20485265
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