YER146W

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Systematic name YER146W
Gene name LSM5
Aliases
Feature type ORF, Verified
Coordinates Chr V:462580..462861
Primary SGDID S000000948


Description of YER146W: Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA[1][2][3]




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References

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  1. Beggs JD (2005) Lsm proteins and RNA processing. Biochem Soc Trans 33(Pt 3):433-8 SGD PMID 15916535
  2. He W and Parker R (2000) Functions of Lsm proteins in mRNA degradation and splicing. Curr Opin Cell Biol 12(3):346-50 SGD PMID 10801455
  3. Kufel J, et al. (2004) Nuclear pre-mRNA decapping and 5' degradation in yeast require the Lsm2-8p complex. Mol Cell Biol 24(21):9646-57 SGD PMID 15485930

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