YAL023C
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| Systematic name | YAL023C |
| Gene name | PMT2 |
| Aliases | FUN25 |
| Feature type | ORF, Verified |
| Coordinates | Chr I:108552..106273 |
| Primary SGDID | S000000021 |
Description of YAL023C: Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein Ser/Thr residues; involved in ER quality control; acts in a complex with Pmt1p, can instead interact with Pmt5; target for new antifungal[1][2][3]
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References
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- ↑ Girrbach V and Strahl S (2003) Members of the evolutionarily conserved PMT family of protein O-mannosyltransferases form distinct protein complexes among themselves. J Biol Chem 278(14):12554-62 SGD PMID 12551906
- ↑ Goder V and Melero A (2011) Protein O-mannosyltransferases participate in ER protein quality control. J Cell Sci 124(Pt 1):144-53 SGD PMID 21147851
- ↑ Lussier M, et al. (1995) Protein O-glycosylation in yeast. The PMT2 gene specifies a second protein O-mannosyltransferase that functions in addition to the PMT1-encoded activity. J Biol Chem 270(6):2770-5 SGD PMID 7852348
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