YEL012W
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| Systematic name | YEL012W | |
| Gene name | UBC8 | |
| Aliases | GID3 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr V:131772..132551 | |
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Description of YEL012W: Ubiquitin-conjugating enzyme that negatively regulates gluconeogenesis by mediating the glucose-induced ubiquitination of fructose-1,6-bisphosphatase (FBPase); cytoplasmic enzyme that catalyzes the ubiquitination of histones in vitro[1][2][3]
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References
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- ↑ Regelmann J, et al. (2003) Catabolite degradation of fructose-1,6-bisphosphatase in the yeast Saccharomyces cerevisiae: a genome-wide screen identifies eight novel GID genes and indicates the existence of two degradation pathways. Mol Biol Cell 14(4):1652-63 SGD PMID 12686616
- ↑ Kaiser P, et al. (1994) A human ubiquitin-conjugating enzyme homologous to yeast UBC8. J Biol Chem 269(12):8797-802 SGD PMID 8132613
- ↑ Qin S, et al. (1991) Cloning and characterization of a Saccharomyces cerevisiae gene encoding a new member of the ubiquitin-conjugating protein family. J Biol Chem 266(23):15549-54 SGD PMID 1869573
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