YDL142C
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| Systematic name | YDL142C | |
| Gene name | CRD1 | |
| Aliases | CLS1 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr IV:202571..201720 | |
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Description of YDL142C: Cardiolipin synthase; produces cardiolipin, which is an important constituent of mitochondrial membranes; required for normal mitochondrial membrane potential and function[1][2][3][4]
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References
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- ↑ Zhang M, et al. (2003) Cardiolipin is not required to maintain mitochondrial DNA stability or cell viability for Saccharomyces cerevisiae grown at elevated temperatures. J Biol Chem 278(37):35204-10 SGD PMID 12840009
- ↑ Jiang F, et al. (1999) Cardiolipin synthase expression is essential for growth at elevated temperature and is regulated by factors affecting mitochondrial development. Mol Microbiol 31(1):373-9 SGD PMID 9987137
- ↑ Jiang F, et al. (2000) Absence of cardiolipin in the crd1 null mutant results in decreased mitochondrial membrane potential and reduced mitochondrial function. J Biol Chem 275(29):22387-94 SGD PMID 10777514
- ↑ Chang SC, et al. (1998) Isolation and characterization of the gene (CLS1) encoding cardiolipin synthase in Saccharomyces cerevisiae. J Biol Chem 273(24):14933-41 SGD PMID 9614098
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