YPR007C

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Systematic name YPR007C
Gene name REC8
Aliases SPO69
Feature type ORF, Verified
Coordinates Chr XVI:571375..569333
Primary SGDID S000006211


Description of YPR007C: Meiosis-specific component of sister chromatid cohesion complex; maintains cohesion between sister chromatids during meiosis I; maintains cohesion between centromeres of sister chromatids until meiosis II; homolog of S. pombe Rec8p[1][2]




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References

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  1. Klein F, et al. (1999) A central role for cohesins in sister chromatid cohesion, formation of axial elements, and recombination during yeast meiosis. Cell 98(1):91-103 SGD PMID 10412984
  2. Buonomo SB, et al. (2000) Disjunction of homologous chromosomes in meiosis I depends on proteolytic cleavage of the meiotic cohesin Rec8 by separin. Cell 103(3):387-98 SGD PMID 11081626

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