YOL061W
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| Systematic name | YOL061W |
| Gene name | PRS5 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:212244..213734 |
| Primary SGDID | S000005422 |
Description of YOL061W: 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes[1][2][3]
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References
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- ↑ Hernando Y, et al. (1999) Genetic analysis and enzyme activity suggest the existence of more than one minimal functional unit capable of synthesizing phosphoribosyl pyrophosphate in Saccharomyces cerevisiae. J Biol Chem 274(18):12480-7 SGD PMID 10212224
- ↑ Hernando Y, et al. (1998) PRS5, the fifth member of the phosphoribosyl pyrophosphate synthetase gene family in Saccharomyces cerevisiae, is essential for cell viability in the absence of either PRS1 or PRS3. J Bacteriol 180(23):6404-7 SGD PMID 9829955
- ↑ Carter AT, et al. (1997) PRS1 is a key member of the gene family encoding phosphoribosylpyrophosphate synthetase in Saccharomyces cerevisiae. Mol Gen Genet 254(2):148-56 SGD PMID 9108276
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