YNL299W
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| Systematic name | YNL299W |
| Gene name | TRF5 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:66517..68445 |
| Primary SGDID | S000005243 |
Description of YNL299W: Non-canonical poly(A) polymerase, involved in nuclear RNA degradation as a component of the TRAMP complex; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; overlapping but non-redundant functions with Pap2p[1][2][3][4][5]
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Contents
Community Commentary
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References
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- ↑ Haracska L, et al. (2005) Trf4 and Trf5 proteins of Saccharomyces cerevisiae exhibit poly(A) RNA polymerase activity but no DNA polymerase activity. Mol Cell Biol 25(22):10183-9 SGD PMID 16260630
- ↑ Egecioglu DE, et al. (2006) Contributions of Trf4p- and Trf5p-dependent polyadenylation to the processing and degradative functions of the yeast nuclear exosome. RNA 12(1):26-32 SGD PMID 16373491
- ↑ Houseley J and Tollervey D (2006) Yeast Trf5p is a nuclear poly(A) polymerase. EMBO Rep 7(2):205-11 SGD PMID 16374505
- ↑ Vanacova S, et al. (2005) A new yeast poly(A) polymerase complex involved in RNA quality control. PLoS Biol 3(6):e189 SGD PMID 15828860
- ↑ LaCava J, et al. (2005) RNA degradation by the exosome is promoted by a nuclear polyadenylation complex. Cell 121(5):713-24 SGD PMID 15935758
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