YNL220W

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Systematic name YNL220W
Gene name ADE12
Aliases BRA9
Feature type ORF, Verified
Coordinates Chr XIV:234414..235715
Primary SGDID S000005164


Description of YNL220W: Adenylosuccinate synthase, catalyzes the first step in synthesis of adenosine monophosphate from inosine 5'monophosphate during purine nucleotide biosynthesis; exhibits binding to single-stranded autonomously replicating (ARS) core sequence[1][2][3]




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References

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  1. Lipps G and Krauss G (1999) Adenylosuccinate synthase from Saccharomyces cerevisiae: homologous overexpression, purification and characterization of the recombinant protein. Biochem J 341 ( Pt 3)():537-43 SGD PMID 10417315
  2. Jones EW and Fink GR (1982) Regulation of amino acid and nucleotide biosynthesis in yeast. Pp.181-299 in The Molecular Biology of the Yeast Saccharomyces: Metabolism and Gene Expression, edited by Strathern JN, Jones EW and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press SGD PMID
  3. Gallert KC, et al. (1996) Enzymatic properties and inhibition by single-stranded autonomously replicating sequences of adenylosuccinate synthase from Saccharomyces cerevisiae. Eur J Biochem 239(2):487-93 SGD PMID 8706758

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