YML007W
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| Systematic name | YML007W |
| Gene name | YAP1 |
| Aliases | PAR1, SNQ3 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:253848..255800 |
| Primary SGDID | S000004466 |
Description of YML007W: Basic leucine zipper (bZIP) transcription factor required for oxidative stress tolerance; activated by H2O2 through the multistep formation of disulfide bonds and transit from the cytoplasm to the nucleus; mediates resistance to cadmium[1][2][3][4]
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References
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- ↑ Moye-Rowley WS, et al. (1989) Yeast YAP1 encodes a novel form of the jun family of transcriptional activator proteins. Genes Dev 3(3):283-92 SGD PMID 2542125
- ↑ Wu A, et al. (1993) Yeast bZip proteins mediate pleiotropic drug and metal resistance. J Biol Chem 268(25):18850-8 SGD PMID 8360174
- ↑ Kuge S, et al. (1997) Regulation of yAP-1 nuclear localization in response to oxidative stress. EMBO J 16(7):1710-20 SGD PMID 9130715
- ↑ Okazaki S, et al. (2007) Multistep disulfide bond formation in Yap1 is required for sensing and transduction of H(2)O(2) stress signal. Mol Cell 27(4):675-88 SGD PMID 17707237
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