YJL034W
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| Systematic name | YJL034W |
| Gene name | KAR2 |
| Aliases | GRP78 |
| Feature type | ORF, Verified |
| Coordinates | Chr X:381321..383369 |
| Primary SGDID | S000003571 |
Description of YJL034W: ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p[1][2][3]
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References
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- ↑ Romisch K (1999) Surfing the Sec61 channel: bidirectional protein translocation across the ER membrane. J Cell Sci 112 ( Pt 23):4185-91 SGD PMID 10564637
- ↑ Tokunaga M, et al. (1992) Purification and characterization of BiP/Kar2 protein from Saccharomyces cerevisiae. J Biol Chem 267(25):17553-9 SGD PMID 1325440
- ↑ Okamura K, et al. (2000) Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast. Biochem Biophys Res Commun 279(2):445-50 SGD PMID 11118306
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